WebLINE-1 ORF-1p increased PXR transcription factor activity by enhancing the cytoplasmic/nuclear translocation of PXR and the recruitment of PXR to the CYP3A4 promoter or enhancer region. LINE-1 ORF-1p may also promote the clearance of sorafenib in HCC cells. Therefore, we conclude that LINE-1 ORF-1p could be a therapeutic target … WebMar 21, 2005 · We found cytoplasmic HuR immunoreactivity in 40% of the 133 invasive ductal breast cancer specimens, and 29% of these samples showed high level of expression. This is in line with our previous data on serous ovarian carcinoma, in which we found cytoplasmic HuR expression in 52% of the cases (8).
Oocyte Maturation - an overview ScienceDirect Topics
WebA typical cyclin is present at low levels for most of the cycle, but increases strongly at the stage where it's needed. M cyclin, for example, peaks dramatically at the transition from … WebA famous example of how cyclins and Cdks work together to control cell cycle transitions is that of maturation-promoting factor (MPF). The name dates back to the 1970s, when researchers found that cells in M phase contained an unknown factor that could force frog egg cells (stuck in G 2 _2 2 start subscript, 2, end subscript phase) to enter M ... hipster term
Signal transduction pathway Cell signaling (article) Khan Academy
WebApr 3, 2024 · A transcription factor usually has one or more DNA-binding domains, and therefore can regulate the expression of multiple genes. Conversely, one gene can be regulated by many transcription factors. ... SCIRR69 is located in the cytoplasm of primary neurons under normal conditions, but it is transferred to the nucleus via shedding from … WebA cytoplasmic factor promoting oocyte maturation: its extraction and preliminary characterization . Science 199 , 1266–1268 (1976). Article Google Scholar WebThe cell-intrinsic properties arise from a cleavage of a cell with asymmetrically expressed maternal cytoplasmic determinants (proteins, small regulatory RNAs and mRNA). Thus, the fate of the cell depends on factors secreted into its cytoplasm during cleavage. homes for sale in metcalf ga